Thymidine-15N2 is the 15N labeled Thymidine, a specific precursor of deoxyribonucleic acid. It is used as a cell synchronizing agent and functions as a DNA synthesis inhibitor, capable of arresting cells at the G1/S boundary prior to DNA replication. Stable heavy isotopes, such as 15N, are incorporated into drug molecules to serve as tracers for quantitation during drug development.
- Used as a tracer and an internal standard for quantitative analysis.
- Can be analyzed by NMR, GC-MS, or LC-MS techniques.
- Functions as a DNA synthesis inhibitor.
- Arrests cells at the G1/S boundary.
- Suitable for metabolic flux analysis.
- Applied in various research areas, including cancer, cell cycle, and anti-infection studies.